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The authors hypothesized that H 2 O 2 formation in the mitochondria results in the inactivation of ATG4, promoting ATG8 lipidation, and thus, activation of autophagy

This enzyme is responsible for the production of uric acid in the body

Notably, the WYRGRL-targeted fluorescent nanoparticles exhibited a 72-fold higher signal after 48 h compared with nanoparticles comprising a scrambled peptide